Cognitive impairments begin early in the high risk period for psychosis and persist throughout the course of illness, leading to significant functional disability. Literature on interventions targeting neurocognition and social cognition in early course psychosis is growing and showing promising results. Effectiveness, predictors, mechanisms, and moderators of these interventions and how they relate to the pathophysiology of early course psychotic disorders is just beginning to be explored. Presenters will share emerging data on novel interventions designed to improve neurocognition and social cognition in patients with early psychosis or those at clinical high risk. Christopher Bowie will present on efficacy and effectiveness of cognitive remediation in patients with early versus long-term psychotic illness. Joseph Ventura will present data on the impact of cognitive remediation on social functioning, and negative and positive symptoms in first episode schizophrenia. Shaun Eack will present on 10-year follow-up data on cognitive enhancement therapy for early course schizophrenia. Michelle Friedman-Yakoobian will describe an adaptation of cognitive enhancement therapy for individuals at clinical high risk for psychosis. Sophia Vinogradov will be the discussant for this symposium and will comment on current progress and future directions for this work.
