Caiying Huang1, Kunxi Xue1, Yanzhen Ren1, Qingwei Li1, Jing Wan1, Jie Zhang1, Baoguo Du1; 1The Third People's Hospital of Zhongshan
Introduction: Emerging evidence suggest that clinical high-risk state for psychosis (CHR) has been increasingly recognized as a critical window for early detection and intervention for psychosis. Available data of prevalence and characteristics in adolescence with CHR from Han Chinese population is limited and variable. Objective: The primary aim of this study is to provide the prevalence and characteristics of Psychosis Risk Syndrome (PRS) in students from the junior middle school of Zhongshan city, Guangdong province, China. Methods: A total 2,157 middle school students aged 12-17 years were enrolled by random and stratified sampling method in Zhongshan. Two stages’ evaluation were employed in this study. In stage I, all participating students in randomly selected schools were recruited to complete the self-reported 16-item version of the Prodromal Questionnaire (PQ-16). In stage II, students met positive criteria (total item score ≧7 or distress score ≧8) were interviewed with the Structured Interview for psychosis-risk Syndromes (SIPS) by a trained psychiatrist. Results: The prevalence of PRS determined by SIPS was 2.7% with 53 of them met the criteria for Attenuated Positive Symptoms Syndrome (APSS) based on the SIPS. The constituent ratios of the most reported symptom in positive, negative and disintegration subscale were 59.3% with perceptual anomalies/hallucinations, 30.5% with learning impairment, and 13.6% with concentration difficulty respectively. Conclusion：It is the first study providing prevalence of PRS in Chinese adolescent populations. Specialized early intervention is warranted for the PRS adolescent populations.
