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Wednesday, October 10 • 3:10pm - 3:20pm
Oral 17, Talk 3. "Autism and Psychosis; Implications for clinical symptoms, quality of life and functioning"

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Katharine Chisholm1, Mirabel Pelton1, Nikita Duncan1, Katherine Kidd1, Klaas Wardenaar2, Rachel Upthegrove3, Matthew Broome1,4, Stephen Wood1,5,6, Ashleigh Lin7; 1Institute of Mental Health, School of Psychology, University of Birmingham, Edgbaston, Birmingham, United Kingdom, 2Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, The Netherlands, 3School of Psychiatry and Institute of Clinical Sciences, University of Birmingham. Forward Thinking Birmingham and Birmingham and Solihull Mental Health Foundation Trust, 4Department of Psychiatry, University of Oxford, UK; Faculty of Philosophy, University of Oxford, UK; Oxford Health NHS Foundation Trust, UK, 5Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Australia, 6Centre for Youth Mental Health, University of Melbourne, Australia, 7Telethon Kids Institute, The University of Western Australia, Perth, Australia
           
There is increasing recognition of the co-occurrence of autism spectrum conditions (ASC) and psychosis, however, there is a lack of evidence regarding the clinical impact this may have. Psychosis and autism are both considered to exist on an extended phenotypic continuum, meaning co-occurrence and overlap at the trait level as well as at the diagnostic level may be important. 99 individuals experiencing a first episode of psychosis took part in the study. Traits of autism were found at elevated rates in the sample and 4 participants had a previous ASC diagnosis. 9.2% of participants had Autism Spectrum Quotient (AQ) scores of >32 (indicative that autism diagnosis is likely) and 28.7% scored >26 (indicative of high autism traits). Higher levels of autistic traits were associated with lower quality of life, lower functioning, and higher levels of current psychotic symptoms. Receiver operating characteristic (ROC) curve analyses indicated that even when autistic trait levels fall below what would be considered diagnostic for ASC, they may still have a significant impact on clinically relevant factors, including quality of life, functioning, and current psychotic symptoms. It is important that psychosis services have systems to adequately address the needs of individuals with higher autistic traits. In particular, it is important that clinical teams support autistic traits and treat psychotic symptoms.



Wednesday October 10, 2018 3:10pm - 3:20pm EDT
St. George AB Westin Copley Place, third floor